What Is MAKTREK® (Bi-Pass Technology) Blend of Probiotic?

MAKTREK® Bi-Pass Technology is a patented delivery system designed to enhance the survivability and effectiveness of probiotics as they pass through the stomach’s harsh, acidic environment. Developed by Maktrek®, this proprietary method is used in various probiotic supplements to ensure that a higher percentage of live microorganisms reach the small intestine, where they can confer the most health benefits.

Traditional probiotic supplements often lose a significant portion of live cultures to stomach acid degradation. The MAKTREK® system aims to solve this by encapsulating probiotics in a gelatinous protective matrix, offering a more reliable way to deliver live bacteria where they’re needed most.

The Science Behind MAKTREK® Bi-Pass Technology

The MAKTREK® delivery method involves a dual-layered system:

1. Prebiotic Base Layer: The first part includes prebiotics that nourish probiotics and help maintain their viability during the encapsulation process and early stages of digestion.
2. Marine Polysaccharide Complex (Bi-Pass Gel Matrix): This is the key feature that forms a natural gel barrier around the probiotic strain when it comes into contact with stomach acid. This gel resists the acidic pH of the stomach and dissolves in the more alkaline environment of the small intestine.

This mechanism mimics the protective mucus in the gastrointestinal tract and allows a greater percentage of live and active probiotic cultures to colonize the gut.

A study published in Beneficial Microbes highlighted how delivery technologies such as encapsulation can significantly increase probiotic survival through the digestive tract (Cook et al., 2012).

Benefits of MAKTREK®-Enhanced Probiotics

1. Improved Probiotic Survivability

One of the main benefits of the MAKTREK® delivery system is its ability to increase the number of viable probiotics that survive stomach acid and reach the intestines. Studies suggest that traditional probiotics can lose up to 90% of their viable cultures before reaching the colon due to degradation in the stomach (Pineiro et al., 2008). MAKTREK® helps preserve more live cultures, enhancing their effectiveness.

2. Enhanced Gut Health

By improving the delivery of live probiotic strains like Lactobacillus and Bifidobacterium, MAKTREK® technology supports a healthier gut microbiome. A balanced gut flora is associated with:

• Improved digestion and nutrient absorption
• Reduced bloating and gas
• Lower incidence of diarrhea or constipation
• Enhanced immunity

According to the World Gastroenterology Organisation (WGO), probiotics can help manage irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and antibiotic-associated diarrhea (WGO, 2017).

3. Immune System Support

Approximately 70–80% of the immune system resides in the gut. Probiotics delivered via MAKTREK® may help regulate immune responses, reduce inflammation, and enhance the body’s ability to fight infections by promoting a balanced intestinal flora.

A review published in Nutrients noted that probiotic supplementation could reduce the duration and severity of respiratory tract infections and improve immune markers (Hao et al., 2015).

4. Potential Mental Health Benefits

Emerging research into the gut-brain axis suggests that gut bacteria can influence mood and cognitive function. Probiotics delivered more effectively with MAKTREK® may contribute to:

• Reduced anxiety and depression symptoms
• Better stress response
• Improved memory and focus

Though more studies are needed, early findings are promising, such as those published in Psychiatry Research (Ng et al., 2018), suggesting a connection between gut microbiota and mental health.

Common Probiotic Strains in MAKTREK® Blends

MAKTREK® is not a probiotic strain itself; rather, it is a delivery method used with common probiotic species, including:

• Lactobacillus acidophilus
• Bifidobacterium lactis
• Lactobacillus plantarum
• Lactobacillus rhamnosus

These strains have well-documented health benefits and are often included in multi-strain blends for synergistic effects.

Formulations and Availability

MAKTREK®-protected probiotics are available in:

• Capsules
• Softgels
• Powdered blends

They are often found in premium probiotic supplements marketed for digestive health, immune support, or women’s health. Labels typically indicate “MAKTREK® Bi-Pass Technology” as a feature for enhanced delivery.

Safety and Considerations

Probiotics delivered using MAKTREK® technology are considered safe for most people. However, those with compromised immune systems, critical illnesses, or recent surgery should consult a healthcare provider before use.

Additional tips for use:

• Store in a cool, dry place or refrigerator to maintain potency
• Take with food for optimal absorption
• Check for allergens in the supplement formulation

Conclusion

MAKTREK® Bi-Pass Technology represents a significant advancement in probiotic supplementation. Enhancing the survival of beneficial bacteria through the digestive tract increases the efficacy and reliability of probiotics for improving gut health, immunity, and potentially even mental well-being.

As the science of the microbiome continues to evolve, delivery systems like MAKTREK® help bridge the gap between lab-tested probiotic strains and real-world health benefits, making them a smart choice for individuals seeking a more effective supplement.

References

• Cook, M. T., Tzortzis, G., Charalampopoulos, D., & Khutoryanskiy, V. V. (2012). Microencapsulation of probiotics for gastrointestinal delivery. Beneficial Microbes, 3(1), 27–37. https://doi.org/10.3920/BM2011.0022
• Pineiro, M., et al. (2008). Criteria for the evaluation of probiotics. Food and Agricultural Organization (FAO).
• World Gastroenterology Organisation (WGO). (2017). Global Guidelines: Probiotics and Prebiotics. https://www.worldgastroenterology.org
• Hao, Q., Dong, B. R., & Wu, T. (2015). Probiotics for preventing acute upper respiratory tract infections. Nutrients, 7(5), 3279–3292. https://doi.org/10.3390/nu7053279
• Ng, Q. X., Peters, C., Ho, C. Y. X., Lim, D. Y., & Yeo, W. S. (2018). A meta-analysis of the use of probiotics to alleviate depressive symptoms. Psychiatry Research, 267, 527–535. https://doi.org/10.1016/j.psychres.2018.06.050